Are Polyglutamine Diseases Expanding?
نویسنده
چکیده
It remains a matter of speculation as to whether the sense CUG-containing RNA and/or the antisense CAG-encoding polyglutamine peptide serves as the pathogenic moiety in Huntington's disease like-2 (HDL2). In this issue of Neuron, Wilburn et al. show that in a HDL2 mouse model, the polyglutamine peptide drives disease progression.
منابع مشابه
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ورودعنوان ژورنال:
- Neuron
دوره 70 شماره
صفحات -
تاریخ انتشار 2011